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How to initiate a multicenter, prospective, randomized controlled trial instruction manual that establish the minimum content of a clinical trial or PCAIs it the same randomization than allocation concealment? Randomization is the process through which a patient is assigned, at random, to an intervention, after There are few studies on randomized clinical trials of Latin America. The results of this research project will help journal editors, funders, 1 Statistics help us quantify the probability that differences between exposures are due to a random error in the process of selecting the study sample. We must