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Tube and bag tips​​ Clean the skin around your tube site with every bandage change. Be sure the tube is taped securely to the skin at all times. Keep the Remove the dressing and clean around the tube with sterile saline using a cotton ball or Q tip. If there is any crusty drainage around the tube, you may clean Instructions for Caring for a Nephrostomy Tube. 1. Wash your hands. Inspect the tube insertion site for signs of infection. See “what to watch for.”.permanent or temporary urinary drainage. The following applies to all patients undergoing insertion or change of a nephrostomy tube. ACUTE CARE SETTING.